Anti-SSH1 antibody (STJA0009808)

SKU:
STJA0009808
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Protein phosphatase Slingshot homolog 1 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SSH1
Gene ID: 54434
Uniprot ID: SSH1_HUMAN
Specificity: This antibody detects endogenous levels of Slingshot homolog 1/SSH1 at Human, Mouse
Immunogen: Synthesized peptide derived from human Slingshot homolog 1/SSH1
Function Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
Protein Name Protein Phosphatase Slingshot Homolog 1
Ssh-Like Protein 1
Ssh-1l
Hssh-1l
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Lamellipodium
Cleavage Furrow
Midbody
Also Recruited To Actin Rich Membrane Protrusions Such As Lamellipodia
Which May Allow Local Control Of Actin Dynamics At Sites Of Cell Locomotion
Also Localized To The Cleavage Furrow And The Midbody During Cytokinesis
Alternative Antibody Names Anti-Protein Phosphatase Slingshot Homolog 1 antibody
Anti-Ssh-Like Protein 1 antibody
Anti-Ssh-1l antibody
Anti-Hssh-1l antibody
Anti-SSH1 antibody
Anti-KIAA1298 antibody
Anti-SSH1L antibody

Information sourced from Uniprot.org

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