Anti-SSB antibody (341-390 aa) (STJ95790)

Name: Anti-SSB antibody (341-390 aa) (STJ95790)
SKU: STJ95790
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenThe antiserum was produced against synthesized peptide derived from the human SSB at the amino acid range 341-390

STJ95790

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Short Description	Rabbit polyclonal anti-Lupus La protein (341-390 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC/IF/ELISA
Host	Rabbit
Reactivity	Human/Rat/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	1 mg/mL
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200
Formulation	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	SSB
Gene ID	6741
Uniprot ID	LA_HUMAN
Immunogen	The antiserum was produced against synthesized peptide derived from the human SSB at the amino acid range 341-390
Immunogen Region	341-390 aa
Specificity	SSB Polyclonal Antibody detects endogenous levels of SSB protein.

Function	Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation.
Protein Name	Lupus La Protein La Autoantigen La Ribonucleoprotein Sjoegren Syndrome Type B Antigen Ss-B
Database Links	Reactome: R-HSA-73980 Reactome: R-HSA-749476
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Lupus La Protein antibody Anti-La Autoantigen antibody Anti-La Ribonucleoprotein antibody Anti-Sjoegren Syndrome Type B Antigen antibody Anti-Ss-B antibody Anti-SSB antibody

Information sourced from Uniprot.org