| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Lupus La protein (341-390 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SSB |
| Gene ID: | 6741 |
| Uniprot ID: | LA_HUMAN |
| Immunogen Region: | 341-390 aa |
| Specificity: | SSB Polyclonal Antibody detects endogenous levels of SSB protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human SSB at the amino acid range 341-390 |
| Function | Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation. |
| Protein Name | Lupus La Protein La Autoantigen La Ribonucleoprotein Sjoegren Syndrome Type B Antigen Ss-B |
| Database Links | Reactome: R-HSA-73980 Reactome: R-HSA-749476 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Lupus La Protein antibody Anti-La Autoantigen antibody Anti-La Ribonucleoprotein antibody Anti-Sjoegren Syndrome Type B Antigen antibody Anti-Ss-B antibody Anti-SSB antibody |
Information sourced from Uniprot.org
