| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | SRXN1 |
| Gene ID: | 140809 |
| Uniprot ID: | SRXN1_HUMAN |
| Immunogen Region: | 1-137 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-137 of human SRXN1 (NP_542763.1). |
| Immunogen Sequence: | MGLRAGGTLGRAGAGRGAPE GPGPSGGAQGGSIHSGRIAA VHNVPLSVLIRPLPSVLDPA KVQSLVDTIREDPDSVPPID VLWIKGAQGGDYFYSFGGCH RYAAYQQLQRETIPAKLVQS TLSDLRVYLGASTPDLQ |
| Tissue Specificity | Widely expressed with highest levels in kidney, lung, spleen and thymus. |
| Function | Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. |
| Protein Name | Sulfiredoxin-1 |
| Database Links | Reactome: R-HSA-9818027 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Sulfiredoxin-1 antibodyAnti-SRXN1 antibodyAnti-C20orf139 antibodyAnti-SRX antibodyAnti-SRX1 antibody |
Information sourced from Uniprot.org
