• Western blot analysis of various lysates, using SRSF4 Rabbit polyclonal antibody (STJ11105724) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-SRSF4 antibody (1-180) (STJ11105724)

SKU:
STJ11105724

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Serine/Arginine-Rich Splicing Factor 4 (1-180) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SRSF4
Gene ID: 6429
Uniprot ID: SRSF4_HUMAN
Immunogen Region: 1-180
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SRSF4 (NP_005617.2).
Immunogen Sequence: MPRVYIGRLSYQARERDVER FFKGYGKILEVDLKNGYGFV EFDDLRDADDAVYELNGKDL CGERVIVEHARGPRRDGSYG SGRSGYGYRRSGRDKYGPPT RTEYRLIVENLSSRCSWQDL KDYMRQAGEVTYADAHKGRK NEGVIEFVSYSDMKRALEKL DGTEVNGRKIRLVEDKPGSR
Post Translational Modifications Extensively phosphorylated on serine residues in the RS domain.
Function Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10.
Protein Name Serine/Arginine-Rich Splicing Factor 4
Pre-Mrna-Splicing Factor Srp75
Srp001lb
Splicing Factor - Arginine/Serine-Rich 4
Database Links Reactome: R-HSA-159236
Reactome: R-HSA-72163
Reactome: R-HSA-72187
Reactome: R-HSA-72203
Reactome: R-HSA-73856
Cellular Localisation Nucleus Speckle
Alternative Antibody Names Anti-Serine/Arginine-Rich Splicing Factor 4 antibody
Anti-Pre-Mrna-Splicing Factor Srp75 antibody
Anti-Srp001lb antibody
Anti-Splicing Factor - Arginine/Serine-Rich 4 antibody
Anti-SRSF4 antibody
Anti-SFRS4 antibody
Anti-SRP75 antibody

Information sourced from Uniprot.org

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