| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SRD5A1/5-alpha reductase 1 (N-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.IHC: In paraffin embedded Human Prostate shows reticulate staining in the cytoplasm of secretory cells in the gland. Recommended concentration: 4-6µg/ml. Paraffin embedded Human Liver. Re |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SRD5A1 |
| Gene ID: | 6715 |
| Uniprot ID: | S5A1_HUMAN |
| Immunogen Region: | N-Term |
| Accession Number: | NP_001038.1 |
| Immunogen Sequence: | ATATGVAEERLLC |
| Function | Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. |
| Protein Name | 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 1Sr Type 1Steroid 5-Alpha-Reductase 1S5ar 1 |
| Database Links | Reactome: R-HSA-193048 |
| Cellular Localisation | Microsome MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 1 antibodyAnti-Sr Type 1 antibodyAnti-Steroid 5-Alpha-Reductase 1 antibodyAnti-S5ar 1 antibodyAnti-SRD5A1 antibody |
Information sourced from Uniprot.org