| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SPTA1 |
| Gene ID: | 6708 |
| Uniprot ID: | SPTA1_HUMAN |
| Immunogen Region: | 940-1160 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 940-1160 of human alpha 1 Spectrin (NP_003117.2). |
| Immunogen Sequence: | KHEAFLLDLNSFGDSMKALR NQANACQQQQAAPVEGVAGE QRVMALYDFQARSPREVTMK KGDVLTLLSSINKDWWKVEA ADHQGIVPAVYVRRLAHDEF PMLPQRRREEPGNITQRQEQ IENQYRSLLDRAEERRRRLL QRYNEFLLAYEAGDMLEWIQ EKKAENTGVELDDVWELQKK FDEFQKDLNTNEPRLRDINK VADDLLFEGLLTPEGAQIRQ E |
| Function | Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. |
| Protein Name | Spectrin Alpha Chain - Erythrocytic 1Erythroid Alpha-Spectrin |
| Database Links | Reactome: R-HSA-375165Reactome: R-HSA-445095Reactome: R-HSA-5673001Reactome: R-HSA-6807878 |
| Cellular Localisation | CytoplasmCytoskeletonCell Cortex |
| Alternative Antibody Names | Anti-Spectrin Alpha Chain - Erythrocytic 1 antibodyAnti-Erythroid Alpha-Spectrin antibodyAnti-SPTA1 antibodyAnti-SPTA antibody |
Information sourced from Uniprot.org