| Short Description : | Rabbit polyclonal anti-Protein sprouty homolog 3 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SPRY3 |
| Gene ID: | 10251 |
| Uniprot ID: | SPY3_HUMAN |
| Immunogen: | Synthesized peptide derived from human SPRY3 |
| Specificity: | This antibody detects endogenous levels of SPRY3 at Human |
| Function | Inhibits neurite branching, arbor length and neurite complexity. Inhibits EGF-mediated p42/44 ERK signaling. Negatively regulates the MAPK cascade, resulting in a reduction of extracellular matrix protein accumulation. May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. |
| Protein Name | Protein Sprouty Homolog 3Spry-3Sprouty Rtk Signaling Antagonist 3Sprouty3 |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Protein Sprouty Homolog 3 antibodyAnti-Spry-3 antibodyAnti-Sprouty Rtk Signaling Antagonist 3 antibodyAnti-Sprouty3 antibodyAnti-SPRY3 antibody |
Information sourced from Uniprot.org
