Anti-SPRED3 antibody (311-361 aa) (STJ194455)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SPRE3 at the amino acid range 311-361
General Information
| Short Description | Rabbit polyclonal anti-Sprouty-related, EVH1 domain-containing protein 3 (311-361 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SPRED3 |
| Gene ID | 399473 |
| Uniprot ID | SPRE3_HUMAN |
| Immunogen | Synthesized peptide derived from the human SPRE3 at the amino acid range 311-361 |
| Immunogen Region | 311-361 aa |
| Specificity | This antibody detects endogenous levels of SPRE3 at Human/Mouse |
Additional Info
| Function | Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase. Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells. |
| Protein Name | Sprouty-Related - Evh1 Domain-Containing Protein 3Spred-3 |
| Database Links | Reactome: R-HSA-5658442Reactome: R-HSA-6802953 |
| Cellular Localisation | Cell MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Sprouty-Related - Evh1 Domain-Containing Protein 3 antibodyAnti-Spred-3 antibodyAnti-SPRED3 antibodyAnti-EVE-3 antibody |
Information sourced from Uniprot.org