| Short Description : | Mouse monoclonal anti-SPR for use in WB, IHC-P and FC in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/FC |
| Host: | Mouse |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 4F5 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Concentration: | 0.31 mg/mL |
| Purification: | Affinity Purified |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100FC 1:50-1:100 |
| Formulation: | Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | SPR |
| Gene ID: | 6697 |
| Uniprot ID: | SPRE_HUMAN |
| Immunogen: | Full length human recombinant protein of human SPR produced in 293T cell. |
| Post Translational Modifications | In vitro phosphorylation of Ser-213 by CaMK2 does not change kinetic parameters. |
| Function | Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin. |
| Protein Name | Sepiapterin ReductaseSpr |
| Database Links | Reactome: R-HSA-1474151Reactome: R-HSA-203615 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Sepiapterin Reductase antibodyAnti-Spr antibodyAnti-SPR antibody |
Information sourced from Uniprot.org
