| Short Description : | Rabbit monoclonal anti-SPINK1 for use in WB and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | R05-4T2 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity Purified |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | SPINK1 |
| Gene ID: | 6690 |
| Uniprot ID: | ISK1_HUMAN |
| Immunogen: | A synthesized peptide derived from human SPINK1 |
| Function | Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens. In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production. |
| Protein Name | Serine Protease Inhibitor Kazal-Type 1Pancreatic Secretory Trypsin InhibitorTumor-Associated Trypsin InhibitorTati |
| Database Links | Reactome: R-HSA-9925561 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Serine Protease Inhibitor Kazal-Type 1 antibodyAnti-Pancreatic Secretory Trypsin Inhibitor antibodyAnti-Tumor-Associated Trypsin Inhibitor antibodyAnti-Tati antibodyAnti-SPINK1 antibodyAnti-PSTI antibody |
Information sourced from Uniprot.org

