Anti-SPIC antibody (131-180 aa) (STJ95749)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human SPIC at the amino acid range 131-180
General Information
| Short Description | Rabbit polyclonal anti-Transcription factor Spi-C (131-180 aa) for use in WB, ELISA and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SPIC |
| Gene ID | 121599 |
| Uniprot ID | SPIC_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human SPIC at the amino acid range 131-180 |
| Immunogen Region | 131-180 aa |
| Specificity | Spi-C Polyclonal Antibody detects endogenous levels of Spi-C protein. |
Additional Info
| Function | Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAAT-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression. |
| Protein Name | Transcription Factor Spi-C |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Spi-C antibodyAnti-SPIC antibody |
Information sourced from Uniprot.org