| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SPATA7 |
| Gene ID: | 55812 |
| Uniprot ID: | SPAT7_HUMAN |
| Immunogen Region: | 300-599 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-599 of human SPATA7 (NP_060888.2). |
| Immunogen Sequence: | MNIKQASNCVTYDAKEKIAP LPLEGHDSTWDEIKDDALQH SSPRAMCQYSLKPPSTRKIY SDEEELLYLSFIEDVTDEIL KLGLFSNRFLERLFERHIKQ NKHLEEEKMRHLLHVLKVDL GCTSEENSVKQNDVDMLNVF DFEKAGNSEPNELKNESEVT IQQERQQYQKALDMLLSAPK DENEIFPSPTEFFMPIYKSK HSEGVIIQQVNDETNLETST LDENHPSISDSLTDRETSV |
| Function | Involved in the maintenance of both rod and cone photoreceptor cells. It is required for recruitment and proper localization of RPGRIP1 to the photoreceptor connecting cilium (CC), as well as photoreceptor-specific localization of proximal CC proteins at the distal CC. Maintenance of protein localization at the photoreceptor-specific distal CC is essential for normal microtubule stability and to prevent photoreceptor degeneration. |
| Protein Name | Spermatogenesis-Associated Protein 7Hsd-3.1Spermatogenesis-Associated Protein Hsd3 |
| Cellular Localisation | CytoplasmCytoskeletonCilium AxonemeCilium Basal BodyCell ProjectionCiliumPhotoreceptor Outer SegmentLocalizes To The Microtubule Network |
| Alternative Antibody Names | Anti-Spermatogenesis-Associated Protein 7 antibodyAnti-Hsd-3.1 antibodyAnti-Spermatogenesis-Associated Protein Hsd3 antibodyAnti-SPATA7 antibodyAnti-HSD3 antibody |
Information sourced from Uniprot.org