Anti-SPACA3 antibody (50-100) {Biotin} (STJ503099)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptides taken within amino acid region 50-100 on human sperm acrosome membrane-associated protein 3 isoform 2.
General Information
| Short Description | Rabbit polyclonal antibody anti-SPACA3 (50-100) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.57 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500ELISA: 1:10, 000IP: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | SPACA3 |
| Gene ID | 124912 |
| Uniprot ID | SACA3_HUMAN |
| Immunogen | Synthetic peptides taken within amino acid region 50-100 on human sperm acrosome membrane-associated protein 3 isoform 2. |
| Immunogen Region | 50-100 |
| Specificity | This antibody will label all isoforms of sperm acrosome membrane-associated protein 3. |
Additional Info
| Tissue Specificity | The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta. |
| Post Translational Modifications | The processed form derives from the membrane form by proteolytic processing. |
| Function | Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro. |
| Protein Name | Sperm Acrosome Membrane-Associated Protein 3Cancer/Testis Antigen 54Ct54Lysozyme-Like Acrosomal Sperm-Specific Secretory Protein Allp-17Lysozyme-Like Protein 3Sperm Lysozyme-Like Protein 1Sperm Protein Reactive With Antisperm AntibodiesSperm Protein Reactive With Asa Cleaved Into - Sperm Acrosome Membrane-Associated Protein 3 - Membrane Form - Sperm Acrosome Membrane-Associated Protein 3 - Processed Form |
| Cellular Localisation | Isoform 1: Cytoplasmic VesicleSecretory VesicleAcrosome MembraneSingle-Pass Type Ii Membrane ProteinAnterior Acrosome In Non-Capacitated Spermatozoa And Retained In The Equatorial Segment And In The Luminal Face Of Both The Inner And Outer Acrosomal Membranes Following Capacitation And The Acrosome ReactionIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Sperm Acrosome Membrane-Associated Protein 3 antibodyAnti-Cancer/Testis Antigen 54 antibodyAnti-Ct54 antibodyAnti-Lysozyme-Like Acrosomal Sperm-Specific Secretory Protein Allp-17 antibodyAnti-Lysozyme-Like Protein 3 antibodyAnti-Sperm Lysozyme-Like Protein 1 antibodyAnti-Sperm Protein Reactive With Antisperm Antibodies antibodyAnti-Sperm Protein Reactive With Asa Cleaved Into - Sperm Acrosome Membrane-Associated Protein 3 - Membrane Form - Sperm Acrosome Membrane-Associated Protein 3 - Processed Form antibodyAnti-SPACA3 antibodyAnti-LYC3 antibodyAnti-LYZL3 antibodyAnti-SLLP1 antibodyAnti-SPRASA antibodyAnti-UNQ424 antibodyAnti-PRO862 antibody |
Information sourced from Uniprot.org