| Short Description : | Rabbit polyclonal antibody anti-SOX2 (250-300) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications: | ELISA/IP/WB |
| Host: | Rabbit |
| Reactivity: | Human/Monkey/Mouse/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Biotin |
| Concentration: | 0.55-0.75 µg/µl |
| Purification: | Affinity Purified |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150 |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Immunogen: | Synthetic peptide taken within amino acid region 250-300 on human Sex determining region Y-box 2 protein. |
| Immunogen Region: | 250-300 |
| Background | Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). |
Information sourced from Uniprot.org