Anti-SOX15 antibody (30-110 aa) (STJ192369)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 30-110
General Information
| Short Description | Rabbit polyclonal anti-Protein SOX-15 (30-110 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SOX15 |
| Gene ID | 6665 |
| Uniprot ID | SOX15_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 30-110 |
| Immunogen Region | 30-110 aa |
| Specificity | SOX15 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Transcription factor that binds to DNA at the 5'-AACAATG-3' consensus sequence. Acts as a transcriptional activator and repressor. Binds synergistically with POU5F1 (OCT3/4) to gene promoters. Binds to the FOXK1 promoter and recruits FHL3, resulting in transcriptional activation of FOXK1 which leads to myoblast proliferation. Acts as an inhibitor of myoblast differentiation via transcriptional repression which leads to down-regulation of the muscle-specific genes MYOD and MYOG. Involved in trophoblast giant cell differentiation via enhancement of HAND1 transcriptional activity. Regulates transcription of HRC via binding to it proximal enhancer region. Involved in skeletal muscle regeneration. Also plays a role in the development of myogenic precursor cells. |
| Protein Name | Transcription Factor Sox-15Protein Sox-12Protein Sox-20Sry-Box Transcription Factor 15 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Sox-15 antibodyAnti-Protein Sox-12 antibodyAnti-Protein Sox-20 antibodyAnti-Sry-Box Transcription Factor 15 antibodyAnti-SOX15 antibodyAnti-SOX12 antibodyAnti-SOX20 antibodyAnti-SOX26 antibodyAnti-SOX27 antibody |
Information sourced from Uniprot.org