Anti-SOX13 antibody (561-611 aa) (STJ195431)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SOX13 at the amino acid range 561-611
General Information
| Short Description | Rabbit polyclonal anti-Transcription factor SOX-13-box 13 (561-611 aa) for use in WB, ELISA and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SOX13 |
| Gene ID | 9580 |
| Uniprot ID | SOX13_HUMAN |
| Immunogen | Synthesized peptide derived from the human SOX13 at the amino acid range 561-611 |
| Immunogen Region | 561-611 aa |
| Specificity | This antibody detects endogenous levels of SOX13 at Human/Mouse |
Additional Info
| Function | Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3'. Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube. Binds to the gene promoter of MBP and acts as a transcriptional repressor. Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells. Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells. Promotes brown adipocyte differentiation. Inhibitor of WNT signaling. |
| Protein Name | Transcription Factor Sox-13Islet Cell Antigen 12SrySex Determining Region Y-Box 13Type 1 Diabetes Autoantigen Ica12 |
| Database Links | Reactome: R-HSA-3769402 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Transcription Factor Sox-13 antibodyAnti-Islet Cell Antigen 12 antibodyAnti-Sry antibodyAnti-Sex Determining Region Y-Box 13 antibodyAnti-Type 1 Diabetes Autoantigen Ica12 antibodyAnti-SOX13 antibody |
Information sourced from Uniprot.org