Anti-SOX1 antibody (292-391) (STJ25659)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SOX1 (292-391) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SOX1 |
| Gene ID | 6656 |
| Uniprot ID | SOX1_HUMAN |
| Immunogen Region | 292-391 |
| Immunogen Sequence | HQNSAVAAAAAAAAASSGAL GALGSLVKSEPSGSPPAPAH SRAPCPGDLREMISMYLPAG EGGDPAAAAAAAAQSRLHSL PQHYQGAGAGVNGTVPLTHI |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 292-391 of human SOX1 (NP_005977.2). |
Additional Info
| Tissue Specificity | Mainly expressed in the developing central nervous system. |
| Function | Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. |
| Protein Name | Transcription Factor Sox-1 |
| Database Links | Reactome: R-HSA-9823739Reactome: R-HSA-9832991 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Sox-1 antibodyAnti-SOX1 antibody |
Information sourced from Uniprot.org