| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SOX1 |
| Gene ID: | 6656 |
| Uniprot ID: | SOX1_HUMAN |
| Immunogen Region: | 292-391 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 292-391 of human SOX1 (NP_005977.2). |
| Immunogen Sequence: | HQNSAVAAAAAAAAASSGAL GALGSLVKSEPSGSPPAPAH SRAPCPGDLREMISMYLPAG EGGDPAAAAAAAAQSRLHSL PQHYQGAGAGVNGTVPLTHI |
| Tissue Specificity | Mainly expressed in the developing central nervous system. |
| Function | Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. |
| Protein Name | Transcription Factor Sox-1 |
| Database Links | Reactome: R-HSA-9823739Reactome: R-HSA-9832991 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Sox-1 antibodyAnti-SOX1 antibody |
Information sourced from Uniprot.org