| Short Description : | Rabbit monoclonal SOX-11 antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | ZR462 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity purified |
| Dilution Range: | 1:100-200 |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | SOX11 |
| Gene ID: | 6664 |
| Uniprot ID: | SOX11_HUMAN |
| Immunogen: | Synthesized human SOX-11 protein |
| Specificity: | Positive Control: Mantle cell lymphoma |
| Tissue Specificity | Expressed primarily in the brain and heart, with low expression in the kidney, pancreas and muscle. |
| Function | Transcription factor that acts as a transcriptional activator. Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation. Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron. Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis. |
| Protein Name | Transcription Factor Sox-11 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Sox-11 antibodyAnti-SOX11 antibody |
Information sourced from Uniprot.org
![Anti-SOX-11 antibody [MRQ-58] (STJ16100461)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/149178/346803/STJ16100461_1__77801.1681998907.jpg?c=1 "Anti-SOX-11 antibody [MRQ-58] (STJ16100461)")
