Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-U5 small nuclear ribonucleoprotein 200 kDa helicase is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SNRNP200 |
Gene ID: |
23020 |
Uniprot ID: |
U520_HUMAN |
Specificity: |
This antibody detects endogenous levels of SNRNP200 at Human |
Immunogen: |
Synthesized peptide derived from human SNRNP200 |
Function | Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome. Plays a role in pre-mRNA splicing as a core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome. |
Protein Name | U5 Small Nuclear Ribonucleoprotein 200 Kda HelicaseActivating Signal Cointegrator 1 Complex Subunit 3-Like 1Brr2 HomologU5 Snrnp-Specific 200 Kda ProteinU5-200kd |
Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-U5 Small Nuclear Ribonucleoprotein 200 Kda Helicase antibodyAnti-Activating Signal Cointegrator 1 Complex Subunit 3-Like 1 antibodyAnti-Brr2 Homolog antibodyAnti-U5 Snrnp-Specific 200 Kda Protein antibodyAnti-U5-200kd antibodyAnti-SNRNP200 antibodyAnti-ASCC3L1 antibodyAnti-BRR2 antibodyAnti-HELIC2 antibodyAnti-KIAA0788 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance