| Host: | Goat |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat/Bovine/Canine/Chicken/Avian/Donkey/Feline/Goat/Guinea Pig/Hamster/Horse/Porcine/Rabbit/Sheep/Simian |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal anti-Synuclein gamma (80aa C-Term) for use in WB in Human, Mouse, Rat, Bovine, Canine, Chicken, Avian, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep and Simian samples. Datasheet included with dilution recom |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Purification: | This antibody is epitope-affinity purified from goat antiserum. |
| Concentration: | 3 mg/mL |
| Dilution Range: | WB 1:500-1:5000 |
| Storage Instruction: | For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours. |
| Gene Symbol: | SNCG |
| Gene ID: | 6623 |
| Uniprot ID: | SYUG_HUMAN |
| Immunogen Region: | 80aa C-Term |
| Accession Number: | ENSG00000173267 |
| Specificity: | Detects endogenous levels of SNCG by Western blot. This Ab is specific for SNCG and does not recognizes SNCA and SNCB proteins. |
| Immunogen: | Purified recombinant peptide derived from within residues 80 aa to the C-terminus of human SNCG produced in E. coli. |
| Immunogen Sequence: | SREEEAENIAVTSGVVRKED REEEAENIAVTSGVVRKEDL EEEAENIAVTSGVVRKEDLR |
| Tissue Specificity | Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung. |
| Post Translational Modifications | Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases. |
| Function | Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway. |
| Protein Name | Gamma-SynucleinBreast Cancer-Specific Gene 1 ProteinPersynSynoretinSr |
| Database Links | |
| Cellular Localisation | CytoplasmPerinuclear RegionCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleAssociated With Centrosomes In Several Interphase CellsIn Mitotic CellsLocalized To The Poles Of The Spindle |
| Alternative Antibody Names | Anti-Gamma-Synuclein antibodyAnti-Breast Cancer-Specific Gene 1 Protein antibodyAnti-Persyn antibodyAnti-Synoretin antibodyAnti-Sr antibodyAnti-SNCG antibodyAnti-BCSG1 antibodyAnti-PERSYN antibodyAnti-PRSN antibody |
Information sourced from Uniprot.org
