Anti-SNAP29 antibody (4-17 aa) [R01-8C8] (STJA0011980)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human SNAP29
General Information
| Short Description | Rabbit monoclonal anti-SNAP29 (4-17 aa) for use in WB, ICC, IF and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-8C8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SNAP29 |
| Gene ID | 9342 |
| Uniprot ID | SNP29_HUMAN |
| Immunogen | A synthetic peptide of human SNAP29 |
| Immunogen Region | 4-17 aa |
Additional Info
| Tissue Specificity | Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. |
| Function | SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions. |
| Protein Name | Synaptosomal-Associated Protein 29Snap-29Soluble 29 Kda Nsf Attachment ProteinVesicle-Membrane Fusion Protein Snap-29 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6811438 |
| Cellular Localisation | CytoplasmGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic VesicleAutophagosome MembraneCell ProjectionCilium MembraneAppears To Be Mostly Membrane-BoundProbably Via Interaction With SyntaxinsBut A Significant Portion Is CytoplasmicLocalizes To The Ciliary Pocket From Where The Cilium Protrudes |
| Alternative Antibody Names | Anti-Synaptosomal-Associated Protein 29 antibodyAnti-Snap-29 antibodyAnti-Soluble 29 Kda Nsf Attachment Protein antibodyAnti-Vesicle-Membrane Fusion Protein Snap-29 antibodyAnti-SNAP29 antibody |
Information sourced from Uniprot.org