Anti-Smooth muscle alpha-actin antibody (N-Term) (STJ70581)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Smooth muscle alpha-actin (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 42kDa band observed in Human and Mouse Duodenum lysates and approx.45kDa in Rat Duodenum lysates (Calculated MW of 42kDa according to Human NP_001604, Mouse NP_031418.1 and Rat |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | ACTA2 |
| Gene ID | 59 |
| Uniprot ID | ACTA_HUMAN |
| Accession Number | NP_001604.1; NP_001135417.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | EEEDSTALVC |
| Specificity | Variants NP_001604.1 and NP_001135417.1 encode the same protein. |
Additional Info
| Function | Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
| Protein Name | Actin - Aortic Smooth MuscleAlpha-Actin-2Cell Growth-Inhibiting Gene 46 Protein Cleaved Into - Actin - Aortic Smooth Muscle - Intermediate Form |
| Database Links | Reactome: R-HSA-445355Reactome: R-HSA-9013695 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Actin - Aortic Smooth Muscle antibodyAnti-Alpha-Actin-2 antibodyAnti-Cell Growth-Inhibiting Gene 46 Protein Cleaved Into - Actin - Aortic Smooth Muscle - Intermediate Form antibodyAnti-ACTA2 antibodyAnti-ACTSA antibodyAnti-ACTVS antibodyAnti-GIG46 antibody |
Information sourced from Uniprot.org