Anti-SMAD9 antibody (Internal) (STJ70900)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-SMAD9 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 50kDa band observed in Human Skin lysates (calculated MW of 48.6kDa according to NP_005896.1). Recommended concentration: 0.3-1.0 µg/ml. Primary incubation was 1 hour.IHC: |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SMAD9 |
| Gene ID | 4093 |
| Uniprot ID | SMAD9_HUMAN |
| Accession Number | NP_005896.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | HSEPLMPHNATYPD |
| Specificity | This antibody is not expected to cross-react with SMAD1 and SMAD5. |
Additional Info
| Post Translational Modifications | Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase. |
| Function | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD). |
| Protein Name | Mothers Against Decapentaplegic Homolog 9Mad Homolog 9Mothers Against Dpp Homolog 9Madh6Smad Family Member 9Smad 9Smad9 |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | CytoplasmNucleusIn The Cytoplasm In The Absence Of LigandMigration To The Nucleus When Complexed With Smad4 |
| Alternative Antibody Names | Anti-Mothers Against Decapentaplegic Homolog 9 antibodyAnti-Mad Homolog 9 antibodyAnti-Mothers Against Dpp Homolog 9 antibodyAnti-Madh6 antibodyAnti-Smad Family Member 9 antibodyAnti-Smad 9 antibodyAnti-Smad9 antibodyAnti-SMAD9 antibodyAnti-MADH6 antibodyAnti-MADH9 antibodyAnti-SMAD8 antibody |
Information sourced from Uniprot.org