Anti-SLURP1 antibody (11-60 aa) (STJ192543)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 11-60
General Information
| Short Description | Rabbit polyclonal anti-Secreted Ly-6/uPAR-related protein 1-81/S (11-60 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLURP1 |
| Gene ID | 57152 |
| Uniprot ID | SLUR1_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 11-60 |
| Immunogen Region | 11-60 aa |
| Specificity | SLUR1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation.the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca(2+) signaling. Seems to have an immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation. |
| Protein Name | Secreted Ly-6/Upar-Related Protein 1Slurp-1Ars Component BArs(Component B-81/SAnti-Neoplastic Urinary ProteinAnup |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Secreted Ly-6/Upar-Related Protein 1 antibodyAnti-Slurp-1 antibodyAnti-Ars Component B antibodyAnti-Ars(Component B-81/S antibodyAnti-Anti-Neoplastic Urinary Protein antibodyAnti-Anup antibodyAnti-SLURP1 antibodyAnti-ARS antibody |
Information sourced from Uniprot.org