| Function | Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation.the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca(2+) signaling. Seems to have an immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation. |
| Protein Name | Secreted Ly-6/Upar-Related Protein 1Slurp-1Ars Component BArs(Component B-81/SAnti-Neoplastic Urinary ProteinAnup |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Secreted Ly-6/Upar-Related Protein 1 antibodyAnti-Slurp-1 antibodyAnti-Ars Component B antibodyAnti-Ars(Component B-81/S antibodyAnti-Anti-Neoplastic Urinary Protein antibodyAnti-Anup antibodyAnti-SLURP1 antibodyAnti-ARS antibody |
Information sourced from Uniprot.org
