Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Secreted Ly-6/uPAR-related protein 1-81/S (11-60 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SLURP1 |
Gene ID: |
57152 |
Uniprot ID: |
SLUR1_HUMAN |
Immunogen Region: |
11-60 aa |
Specificity: |
SLUR1 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 11-60 |
Function | Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation.the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca(2+) signaling. Seems to have an immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation. |
Protein Name | Secreted Ly-6/Upar-Related Protein 1Slurp-1Ars Component BArs(Component B-81/SAnti-Neoplastic Urinary ProteinAnup |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Secreted Ly-6/Upar-Related Protein 1 antibodyAnti-Slurp-1 antibodyAnti-Ars Component B antibodyAnti-Ars(Component B-81/S antibodyAnti-Anti-Neoplastic Urinary Protein antibodyAnti-Anup antibodyAnti-SLURP1 antibodyAnti-ARS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance