• Western blot with Anti-SLC9A3 Antibody (STJ503056) with SLC9A3 peptide. Antibody at 1:500 dilution in buffer.

Anti-SLC9A3 antibody (790-835) (STJ503056)

SKU:
STJ503056-100

Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: ELISA/WB
Reactivity: Human/Monkey/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SLC9A3 (790-835) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.68 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SLC9A3
Gene ID: 6550
Uniprot ID: SL9A3_HUMAN
Immunogen Region: 790-835
Immunogen: Synthetic peptide taken within amino acid region 790-835 on Slc9A3 protein.
Post Translational Modifications Phosphorylated by PKA, which inhibits activity. Phosphorylation at Ser-663 by SGK1 is associated with increased abundance at the cell membrane. Phosphorylation at Ser-718 by CSNK2A1 regulates SLC9A3 activity through the formation of multiple signaling complexes.
Function Plasma membrane Na(+)/H(+) antiporter. Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis. Major apical Na(+)/H(+) exchanger in kidney and intestine playing an important role in renal and intestine Na(+) absorption and blood pressure regulation.
Protein Name Sodium/Hydrogen Exchanger 3
Na(+/H(+ Exchanger 3
Nhe-3
Solute Carrier Family 9 Member 3
Database Links Reactome: R-HSA-425986
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Recycling Endosome Membrane
Early Endosome Membrane
In Intestinal Epithelial Cells
Localizes To The Ileal Brush Border
Phosphorylation At Ser-663 By Sgk1 Is Associated With Increased Abundance At The Cell Membrane
Angiotensin-2 Enhances Apical Expression
Alternative Antibody Names Anti-Sodium/Hydrogen Exchanger 3 antibody
Anti-Na(+/H(+ Exchanger 3 antibody
Anti-Nhe-3 antibody
Anti-Solute Carrier Family 9 Member 3 antibody
Anti-SLC9A3 antibody
Anti-NHE3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance