| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC6A9 |
| Gene ID: | 6536 |
| Uniprot ID: | SC6A9_HUMAN |
| Immunogen Region: | 1-110 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SLC6A9 (NP_964012.2). |
| Immunogen Sequence: | MSGGDTRAAIARPRMAAAHG PVAPSSPEQVTLLPVQRSFF LPPFSGATPSTSLAESVLKV WHGAYNSGLLPQLMAQHSLA MAQNGAVPSEATKRDQNLKR GNWGNQIEFV |
| Tissue Specificity | Isoform GlyT-1A: Expressed in the brain, kidney, pancreas, lung, placenta and liver. Isoform GlyT-1B: Expressed in the brain, kidney, pancreas, lung, placenta and liver. Isoform GlyT-1C: Expressed only in the brain. |
| Function | Sodium- and chloride-dependent glycine transporter. Essential for regulating glycine concentrations at inhibitory glycinergic synapses. Isoform GlyT-1B: Sodium- and chloride-dependent glycine transporter. Isoform GlyT-1C: Sodium- and chloride-dependent glycine transporter. |
| Protein Name | Sodium- And Chloride-Dependent Glycine Transporter 1Glyt-1Glyt1Solute Carrier Family 6 Member 9 |
| Database Links | Reactome: R-HSA-442660 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium- And Chloride-Dependent Glycine Transporter 1 antibodyAnti-Glyt-1 antibodyAnti-Glyt1 antibodyAnti-Solute Carrier Family 6 Member 9 antibodyAnti-SLC6A9 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and TXNDC9 knockout (KO) HeLa cells, using [KO Validated] TXNDC9 Rabbit polyclonal antibody (STJ11100745) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89683/358174/STJ11100745_1__65395.1713122481.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TXNDC9 knockout (KO) HeLa cells, using [KO Validated] TXNDC9 Rabbit polyclonal antibody (STJ11100745) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
