| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SLC6A8 (580-630 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SLC6A8 |
| Gene ID: | 6535 |
| Uniprot ID: | SC6A8_HUMAN |
| Immunogen Region: | 580-630 aa |
| Specificity: | Specific for SLC6A8. |
| Immunogen: | A synthetic peptide from aa region 580-630 of human SLC6A8 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse. |
| Post Translational Modifications | Glycosylated. |
| Function | Creatine:sodium symporter which mediates the uptake of creatine. Plays an important role in supplying creatine to the brain via the blood-brain barrier. |
| Protein Name | Sodium- And Chloride-Dependent Creatine Transporter 1Ct1Creatine Transporter 1Solute Carrier Family 6 Member 8 |
| Database Links | Reactome: R-HSA-71288 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Sodium- And Chloride-Dependent Creatine Transporter 1 antibodyAnti-Ct1 antibodyAnti-Creatine Transporter 1 antibodyAnti-Solute Carrier Family 6 Member 8 antibodyAnti-SLC6A8 antibody |
Information sourced from Uniprot.org