| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC6A8 |
| Gene ID: | 6535 |
| Uniprot ID: | SC6A8_HUMAN |
| Immunogen Region: | 539-635 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 539-635 of human SLC6A8 (NP_005620.1). |
| Immunogen Sequence: | VVYYEPLVYNNTYVYPWWGE AMGWAFALSSMLCVPLHLLG CLLRAKGTMAERWQHLTQPI WGLHHLEYRAQDADVRGLTT LTPVSESSKVVVVESVM |
| Tissue Specificity | Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate. |
| Post Translational Modifications | Glycosylated. |
| Function | Creatine:sodium symporter which mediates the uptake of creatine. Plays an important role in supplying creatine to the brain via the blood-brain barrier. |
| Protein Name | Sodium- And Chloride-Dependent Creatine Transporter 1Ct1Creatine Transporter 1Solute Carrier Family 6 Member 8 |
| Database Links | Reactome: R-HSA-71288 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Sodium- And Chloride-Dependent Creatine Transporter 1 antibodyAnti-Ct1 antibodyAnti-Creatine Transporter 1 antibodyAnti-Solute Carrier Family 6 Member 8 antibodyAnti-SLC6A8 antibody |
Information sourced from Uniprot.org