Anti-SLC6A3 antibody (550-600) {FITC} (STJ500737)

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STJ500737-100
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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-SLC6A3 (550-600) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Polyclonal
Conjugation: FITC
Isotype: IgG
Formulation: Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Purification: Affinity Purified
Concentration: 0.50 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:50-1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SLC6A3
Gene ID: 6531
Uniprot ID: SC6A3_HUMAN
Immunogen Region: 550-600
Immunogen: Synthetic peptide taken within amino acid region 550-600 on SLC6A3 protein.
Tissue Specificity Highly expressed in substantia nigra. Expressed in axonal varicosities in dopaminergic nerve terminals (at protein level). Expressed in the striatum (at protein level).
Function Mediates sodium- and chloride-dependent transport of dopamine. Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling.
Protein Name Sodium-Dependent Dopamine Transporter
Da Transporter
Dat
Solute Carrier Family 6 Member 3
Database Links Reactome: R-HSA-379401
Reactome: R-HSA-442660
Reactome: R-HSA-5619081
Reactome: R-HSA-5660724
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Neuron Projection
Axon
Localizes To Neurite Tips In Neuronal Cells
Colocalizes With Septin4 At Axon Terminals
Especially At The Varicosities
Alternative Antibody Names Anti-Sodium-Dependent Dopamine Transporter antibody
Anti-Da Transporter antibody
Anti-Dat antibody
Anti-Solute Carrier Family 6 Member 3 antibody
Anti-SLC6A3 antibody
Anti-DAT1 antibody

Information sourced from Uniprot.org

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