| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Sodium-dependent neutral amino acid transporter B0AT1 neutral amino acid transporter AT1 is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC6A19 |
| Gene ID: | 340024 |
| Uniprot ID: | S6A19_HUMAN |
| Specificity: | S6A19 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Function | Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells. This uptake is sodium-dependent and chloride-independent. Requires CLTRN in kidney or ACE2 in intestine for cell surface expression and amino acid transporter activity. |
| Protein Name | Sodium-Dependent Neutral Amino Acid Transporter B(0at1 Solute Carrier Family 6 Member 19 System B(0 Neutral Amino Acid Transporter At1 |
| Database Links | Reactome: R-HSA-352230 Reactome: R-HSA-442660 Reactome: R-HSA-5619044 Reactome: R-HSA-5659735 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Apical Cell Membrane Colocalizes With Ace2 On The Apical Membrane Of Cells Lining Villi Of The Jejunum Ileum And On Kidney Proximal Tubules |
| Alternative Antibody Names | Anti-Sodium-Dependent Neutral Amino Acid Transporter B(0at1 antibody Anti-Solute Carrier Family 6 Member 19 antibody Anti-System B(0 Neutral Amino Acid Transporter At1 antibody Anti-SLC6A19 antibody Anti-B0AT1 antibody |
Information sourced from Uniprot.org