| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Sodium-dependent neutral amino acid transporter B0AT1 neutral amino acid transporter AT1 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC6A19 |
| Gene ID: | 340024 |
| Uniprot ID: | S6A19_HUMAN |
| Specificity: | S6A19 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Function | Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells. This uptake is sodium-dependent and chloride-independent. Requires CLTRN in kidney or ACE2 in intestine for cell surface expression and amino acid transporter activity. |
| Protein Name | Sodium-Dependent Neutral Amino Acid Transporter B(0at1Solute Carrier Family 6 Member 19System B(0 Neutral Amino Acid Transporter At1 |
| Database Links | Reactome: R-HSA-352230Reactome: R-HSA-442660Reactome: R-HSA-5619044Reactome: R-HSA-5659735 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneColocalizes With Ace2 On The Apical Membrane Of Cells Lining Villi Of The JejunumIleum And On Kidney Proximal Tubules |
| Alternative Antibody Names | Anti-Sodium-Dependent Neutral Amino Acid Transporter B(0at1 antibodyAnti-Solute Carrier Family 6 Member 19 antibodyAnti-System B(0 Neutral Amino Acid Transporter At1 antibodyAnti-SLC6A19 antibodyAnti-B0AT1 antibody |
Information sourced from Uniprot.org
