| Short Description : | Rabbit polyclonal antibody anti-SLC5A2 (580-630) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications: | CM/ELISA/ICC/IF/IHC/IP/WB |
| Host: | Rabbit |
| Reactivity: | Human/Monkey/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.65 µg/µl |
| Purification: | Affinity Purified |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150IHC: 1:50ICC: 1:50IF: 1:50CFM: 1:50 |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | SLC5A2 |
| Gene ID: | 6524 |
| Uniprot ID: | SC5A2_HUMAN |
| Immunogen: | Synthetic peptide taken within amino acid region 580-630 on human SGLT2 protein. |
| Immunogen Region: | 580-630 |
| Function | Electrogenic Na(+)-coupled sugar symporter that actively transports D-glucose at the plasma membrane, with a Na(+) to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump. Unlike SLC5A1/SGLT1, requires the auxiliary protein PDZK1IP1/MAP17 for full transporter activity. Has a primary role in D-glucose reabsorption from glomerular filtrate across the brush border of the early proximal tubules of the kidney. |
| Protein Name | Sodium/Glucose Cotransporter 2Na(+/Glucose Cotransporter 2Low Affinity Sodium-Glucose CotransporterSolute Carrier Family 5 Member 2 |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-5658208 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium/Glucose Cotransporter 2 antibodyAnti-Na(+/Glucose Cotransporter 2 antibodyAnti-Low Affinity Sodium-Glucose Cotransporter antibodyAnti-Solute Carrier Family 5 Member 2 antibodyAnti-SLC5A2 antibodyAnti-SGLT2 antibody |
Information sourced from Uniprot.org
