Function | Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina. |
Protein Name | Sodium-Coupled Monocarboxylate Transporter 2Electroneutral Sodium Monocarboxylate CotransporterLow-Affinity Sodium-Lactate CotransporterSolute Carrier Family 5 Member 12 |
Database Links | Reactome: R-HSA-427601 |
Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinDetected At The Brush Border Membrane Of The KidneyColocalizes With Viementin In Mueller Cells |
Alternative Antibody Names | Anti-Sodium-Coupled Monocarboxylate Transporter 2 antibodyAnti-Electroneutral Sodium Monocarboxylate Cotransporter antibodyAnti-Low-Affinity Sodium-Lactate Cotransporter antibodyAnti-Solute Carrier Family 5 Member 12 antibodyAnti-SLC5A12 antibodyAnti-SMCT2 antibody |
Information sourced from Uniprot.org