| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Heme transporter HRG1 (28-78 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC48A1 |
| Gene ID: | 55652 |
| Uniprot ID: | HRG1_HUMAN |
| Immunogen Region: | 28-78 aa |
| Specificity: | This antibody detects endogenous levels of HRG1 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human HRG1 at the amino acid range 28-78 |
| Function | Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. In macrophages of the reticuloendothelial system, is the heme transporter for heme-iron recycling. Essential for macrophage iron homeostasis, transports heme from the phagolysosome to the cytoplasm during erythrophagocytosis (EP). |
| Protein Name | Heme Transporter Hrg1Heme-Responsive Gene 1 Protein HomologHrg-1Hhrg-1Solute Carrier Family 48 Member 1 |
| Cellular Localisation | Endosome MembraneMulti-Pass Membrane ProteinLysosome MembraneCytoplasmic VesiclePhagosome MembraneIn MacrophagesSpecifically Localizes To The Phagolysosomal Membranes During Erythrophagocytosis |
| Alternative Antibody Names | Anti-Heme Transporter Hrg1 antibodyAnti-Heme-Responsive Gene 1 Protein Homolog antibodyAnti-Hrg-1 antibodyAnti-Hhrg-1 antibodyAnti-Solute Carrier Family 48 Member 1 antibodyAnti-SLC48A1 antibodyAnti-HRG1 antibody |
Information sourced from Uniprot.org
