Function | Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine. May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake. Isoform 1: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine. Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane. Isoform 2: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine. Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane. |
Protein Name | Equilibrative Nucleobase Transporter 1Protein Foap-13Solute Carrier Family 43 Member 3 |
Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Equilibrative Nucleobase Transporter 1 antibodyAnti-Protein Foap-13 antibodyAnti-Solute Carrier Family 43 Member 3 antibodyAnti-SLC43A3 antibodyAnti-ENBT1 antibodyAnti-PSEC0252 antibody |
Information sourced from Uniprot.org