| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SLC39A1 (1st Cytoplasmic Domain) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SLC39A1 |
| Gene ID: | 27173 |
| Uniprot ID: | S39A1_HUMAN |
| Immunogen Region: | 1st Cytoplasmic Domain |
| Specificity: | Specific for SLC39A1. |
| Immunogen: | A synthetic peptide from 1t cytoplasmic domain of human Zinc transporter ZIP1 (SLC39A1, ZIP1) conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Transporter for the divalent cation Zn(2+). Mediates the influx of Zn(2+) into cells from extracellular space. Functions as the major importer of zinc from circulating blood plasma into prostate cells. |
| Protein Name | Zinc Transporter Zip1Solute Carrier Family 39 Member 1Zinc-Iron-Regulated Transporter-LikeZrt- And Irt-Like Protein 1Zip-1Hzip1 |
| Database Links | Reactome: R-HSA-442380 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum MembraneShows A Vesicular Localization Corresponding Partially To The Endoplasmic Reticulum In Several Epithelial Cell Lines |
| Alternative Antibody Names | Anti-Zinc Transporter Zip1 antibodyAnti-Solute Carrier Family 39 Member 1 antibodyAnti-Zinc-Iron-Regulated Transporter-Like antibodyAnti-Zrt- And Irt-Like Protein 1 antibodyAnti-Zip-1 antibodyAnti-Hzip1 antibodyAnti-SLC39A1 antibodyAnti-IRT1 antibodyAnti-ZIP1 antibodyAnti-ZIRTL antibodyAnti-CGI-08 antibodyAnti-CGI-71 antibody |
Information sourced from Uniprot.org