| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
SLC38A4 |
| Gene ID: |
55089 |
| Uniprot ID: |
S38A4_HUMAN |
| Immunogen Region: |
1-70 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human SLC38A4 (NP_060488.2). |
| Immunogen Sequence: |
MDPMELRNVNIEPDDESSSG ESAPDSYIGIGNSEKAAMSS QFANEDTESQKFLTNGFLGK KKLADYADEH |
| Tissue Specificity | Expressed almost exclusively in embryonic and adult liver, and at lower levels in the kidney. Expressed at lower levels in adult muscle and pancreas. Detected in fetal blood vessels. Expressed in syncytiotrophoblas of placenta during first trimester and at term. Highly expressed in first trimester placenta compared to term placenta. |
| Post Translational Modifications | The disulfide bond plays an important role in substrate transport, but has no effect on trafficking to the cell surface. |
| Function | Symporter that cotransports neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane. The transport is electrogenic, pH dependent and partially tolerates substitution of Na(+) by Li(+). Preferentially transports smaller amino acids, such as glycine, L-alanine, L-serine, L-asparagine and L-threonine, followed by L-cysteine, L-histidine, L-proline and L-glutamine and L-methionine. |
| Protein Name | Sodium-Coupled Neutral Amino Acid Transporter 4Amino Acid Transporter A3Na(+-Coupled Neutral Amino Acid Transporter 4Solute Carrier Family 38 Member 4System A Amino Acid Transporter 3System N Amino Acid Transporter 3 |
| Database Links | Reactome: R-HSA-352230 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionMicrovillus MembraneMicrovillus Membrane Localization In Placenta |
| Alternative Antibody Names | Anti-Sodium-Coupled Neutral Amino Acid Transporter 4 antibodyAnti-Amino Acid Transporter A3 antibodyAnti-Na(+-Coupled Neutral Amino Acid Transporter 4 antibodyAnti-Solute Carrier Family 38 Member 4 antibodyAnti-System A Amino Acid Transporter 3 antibodyAnti-System N Amino Acid Transporter 3 antibodyAnti-SLC38A4 antibodyAnti-ATA3 antibodyAnti-NAT3 antibodyAnti-SNAT4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
