Anti-SLC35D3 antibody (310-390) (STJ119889)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC35D3 (310-390) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC35D3 |
| Gene ID | 340146 |
| Uniprot ID | S35D3_HUMAN |
| Immunogen Region | 310-390 |
| Immunogen Sequence | NYEDLEAQPRGEEAQLSGDQ LPFVMEELPGEGGNGRSEGG EAAGGPAQESRQEVRGSPRG VPLVAGSSEEGSRRSLKDAY L |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 310-390 of human SLC35D3 (NP_001008783.1). |
Additional Info
| Function | Probable UDP-glucose transmembrane transporter involved in UDP-glucose transport from the cytosol to the lumen of synaptic vesicles. It is involved in platelet dense granules maturation. Alternatively, could function as a molecular adapter enhancing the formation of the PI3KC3-C1/AIC/autophagy initiation complex to promote autophagy in dopaminergic neurons. Could also regulate the plasma membrane localization of the D(1A) dopamine receptor/DRD1 and dopamine signaling. |
| Protein Name | Solute Carrier Family 35 Member D3Fringe Connection-Like Protein 1 |
| Database Links | |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMulti-Pass Membrane ProteinEarly Endosome MembraneEndoplasmic Reticulum MembraneActive At Early Endosome Membrane In The Biosynthesis Of Mature Platelet-Dense Granules |
| Alternative Antibody Names | Anti-Solute Carrier Family 35 Member D3 antibodyAnti-Fringe Connection-Like Protein 1 antibodyAnti-SLC35D3 antibodyAnti-FRCL1 antibody |
Information sourced from Uniprot.org