| Short Description : | Rabbit polyclonal SLC35D3 (310-390) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC35D3 |
| Gene ID: | 340146 |
| Uniprot ID: | S35D3_HUMAN |
| Immunogen Region: | 310-390 |
| Immunogen Sequence: | NYEDLEAQPRGEEAQLSGDQ LPFVMEELPGEGGNGRSEGG EAAGGPAQESRQEVRGSPRG VPLVAGSSEEGSRRSLKDAY L |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 310-390 of human SLC35D3 (NP_001008783.1). |
| Function | Probable UDP-glucose transmembrane transporter involved in UDP-glucose transport from the cytosol to the lumen of synaptic vesicles. It is involved in platelet dense granules maturation. Alternatively, could function as a molecular adapter enhancing the formation of the PI3KC3-C1/AIC/autophagy initiation complex to promote autophagy in dopaminergic neurons. Could also regulate the plasma membrane localization of the D(1A) dopamine receptor/DRD1 and dopamine signaling. |
| Protein Name | Solute Carrier Family 35 Member D3Fringe Connection-Like Protein 1 |
| Database Links | |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMulti-Pass Membrane ProteinEarly Endosome MembraneEndoplasmic Reticulum MembraneActive At Early Endosome Membrane In The Biosynthesis Of Mature Platelet-Dense Granules |
| Alternative Antibody Names | Anti-Solute Carrier Family 35 Member D3 antibodyAnti-Fringe Connection-Like Protein 1 antibodyAnti-SLC35D3 antibodyAnti-FRCL1 antibody |
Information sourced from Uniprot.org
