| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SLC30A8 (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SLC30A8 |
| Gene ID: | 169026 |
| Uniprot ID: | ZNT8_HUMAN |
| Immunogen Region: | N-Term |
| Specificity: | Specific for SLC30A8. |
| Immunogen: | A synthetic peptide from n-terminal region of human Zinc transporter 8 (SLC30A8, ZNT8) conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion. |
| Protein Name | Proton-Coupled Zinc Antiporter Slc30a8Solute Carrier Family 30 Member 8Zinc Transporter 8Znt-8 |
| Database Links | Reactome: R-HSA-264876Reactome: R-HSA-435368 |
| Cellular Localisation | Cytoplasmic VesicleSecretory Vesicle MembraneMulti-Pass Membrane ProteinCell MembraneAssociated With Insulin And Glucagon Secretory Granules |
| Alternative Antibody Names | Anti-Proton-Coupled Zinc Antiporter Slc30a8 antibodyAnti-Solute Carrier Family 30 Member 8 antibodyAnti-Zinc Transporter 8 antibodyAnti-Znt-8 antibodyAnti-SLC30A8 antibodyAnti-ZNT8 antibody |
Information sourced from Uniprot.org