| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Proton-coupled zinc antiporter SLC30A8 (171-220 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC30A8 |
| Gene ID: | 169026 |
| Uniprot ID: | ZNT8_HUMAN |
| Immunogen Region: | 171-220 aa |
| Specificity: | ZnT-8 Polyclonal Antibody detects endogenous levels of ZnT-8 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human SLC30A8 at the amino acid range 171-220 |
| Function | Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion. |
| Protein Name | Proton-Coupled Zinc Antiporter Slc30a8Solute Carrier Family 30 Member 8Zinc Transporter 8Znt-8 |
| Database Links | Reactome: R-HSA-264876Reactome: R-HSA-435368 |
| Cellular Localisation | Cytoplasmic VesicleSecretory Vesicle MembraneMulti-Pass Membrane ProteinCell MembraneAssociated With Insulin And Glucagon Secretory Granules |
| Alternative Antibody Names | Anti-Proton-Coupled Zinc Antiporter Slc30a8 antibodyAnti-Solute Carrier Family 30 Member 8 antibodyAnti-Zinc Transporter 8 antibodyAnti-Znt-8 antibodyAnti-SLC30A8 antibodyAnti-ZNT8 antibody |
Information sourced from Uniprot.org