| Host: |
Rabbit |
| Applications: |
IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Proton-coupled zinc antiporter SLC30A2 (150-200 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC30A2 |
| Gene ID: |
7780 |
| Uniprot ID: |
ZNT2_HUMAN |
| Immunogen Region: |
150-200 aa |
| Specificity: |
ZnT-2 Polyclonal Antibody detects endogenous levels of ZnT-2 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human SLC30A2 at the amino acid range 150-200 |
| Function | Isoform 1: Electroneutral proton-coupled antiporter concentrating zinc ions into a variety of intracellular organelles including endosomes, zymogen granules and mitochondria. Thereby, plays a crucial role in cellular zinc homeostasis to confer upon cells protection against its potential cytotoxicity. Regulates the zinc concentration of milk, through the transport of zinc ions into secretory vesicles of mammary cells. By concentrating zinc ions into lysosomes participates to lysosomal-mediated cell death during early mammary gland involution. Isoform 2: Electroneutral proton-coupled antiporter mediating the efflux of zinc ions through the plasma membrane. |
| Protein Name | Proton-Coupled Zinc Antiporter Slc30a2Solute Carrier Family 30 Member 2Zinc Transporter 2Znt-2 |
| Database Links | Reactome: R-HSA-435368 |
| Cellular Localisation | Isoform 1: Cytoplasmic VesicleSecretory Vesicle MembraneMulti-Pass Membrane ProteinZymogen Granule MembraneEndosome MembraneLysosome MembraneMitochondrion Inner MembraneLocalization To Lysosomes Is Induced By Tnf-AlphaIsoform 2: Cell Membrane |
| Alternative Antibody Names | Anti-Proton-Coupled Zinc Antiporter Slc30a2 antibodyAnti-Solute Carrier Family 30 Member 2 antibodyAnti-Zinc Transporter 2 antibodyAnti-Znt-2 antibodyAnti-SLC30A2 antibodyAnti-ZNT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
