| Tissue Specificity | Isoform 1: Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Detected in kidney membrane (at protein level). Isoform 2: Only detected in the apical membranes of polarized renal tubular cells and placenta. Detected in kidney membrane (at protein level). |
| Function | High-capacity urate transporter, which may play a role in the urate reabsorption by proximal tubules. May have a residual high-affinity, low-capacity glucose and fructose transporter activity. Transports urate at rates 45- to 60-fold faster than glucose. Does not transport galactose. May mediate small uptake of adenine but not of other nucleobases. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 9Glucose Transporter Type 9Glut-9Urate Transporter |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-5619047 |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneIsoform 2: Cell MembraneApical Cell Membrane |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 9 antibodyAnti-Glucose Transporter Type 9 antibodyAnti-Glut-9 antibodyAnti-Urate Transporter antibodyAnti-SLC2A9 antibodyAnti-GLUT9 antibody |
Information sourced from Uniprot.org
