| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC2A5 (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC2A5 |
| Gene ID: |
6518 |
| Uniprot ID: |
GTR5_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC2A5 (NP_003030.1). |
| Immunogen Sequence: |
MEQQDQSMKEGRLTLVLALA TLIAAFGSSFQYGYNVAAVN SPALLMQQFYNETYYGRTGE FMEDFPLTLLWSVTVSMFPF GGFIGSLLVGPLVNKFGRKG |
| Tissue Specificity | Detected in skeletal muscle, and in jejunum brush border membrane and basolateral membrane (at protein level). Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue. |
| Function | Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of 2-deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 5Fructose TransporterGlucose Transporter Type 5 - Small IntestineGlut-5 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8981373 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinCell MembraneSarcolemmaLocalized On The Apical Membrane Of Jejunum VilliBut Also On Lateral Plasma Membranes Of The VilliTransport To The Cell Membrane Is Dependent On Rab11a |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 5 antibodyAnti-Fructose Transporter antibodyAnti-Glucose Transporter Type 5 - Small Intestine antibodyAnti-Glut-5 antibodyAnti-SLC2A5 antibodyAnti-GLUT5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
