Host: |
Sheep |
Applications: |
CM/ELISA/ICC/IF/IHC/IP/WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Sheep polyclonal antibody anti-SLC2A1 is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Purification: |
Affinity Purified |
Concentration: |
0.5 µg/µl |
Dilution Range: |
WB: 1:5, 000DB: 1:12, 000ELISA: 1:12, 000IP: 1:200IHC: 1:200ICC: 1:200IF: 1:200CFM: 1:200 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
SLC2A1 |
Gene ID: |
6513 |
Uniprot ID: |
GTR1_HUMAN |
Immunogen: |
Synthetic peptide corresponding to unique amino acid sequences on GLUT1 protein. |
Tissue Specificity | Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues. |
Post Translational Modifications | Phosphorylation at Ser-226 by PKC promotes glucose uptake by increasing cell membrane localization. |
Function | Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity.can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation. |
Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1Glucose Transporter Type 1 - Erythrocyte/BrainGlut-1Hepg2 Glucose Transporter |
Database Links | Reactome: R-HSA-189200Reactome: R-HSA-196836Reactome: R-HSA-422356Reactome: R-HSA-5619043Reactome: R-HSA-5653890 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinMelanosomePhotoreceptor Inner SegmentLocalizes Primarily At The Cell SurfaceIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1 antibodyAnti-Glucose Transporter Type 1 - Erythrocyte/Brain antibodyAnti-Glut-1 antibodyAnti-Hepg2 Glucose Transporter antibodyAnti-SLC2A1 antibodyAnti-GLUT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance