Anti-SLC29A2 antibody (230-280 aa) (STJ13102235)

SKU:
STJ13102235-100
£331.50
Free Shipping
Processing The item has been added

Host: Rabbit
Applications: IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-SLC29A2 (230-280 aa) is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Lyophilised
Purification: IgG purified
Dilution Range: IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage Instruction: Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol: SLC29A2
Gene ID: 3177
Uniprot ID: S29A2_HUMAN
Immunogen Region: 230-280 aa
Specificity: Specific for SLC29A2.
Immunogen: A synthetic peptide from aa region 230-280 of human SLC29A2 conjugated to an immunogenic carrier protein was used as the antigen.
Post Translational Modifications Glycosylated.
Function Bidirectional uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent, passive transporter. Involved in the transport of nucleosides such as inosine, adenosine, uridine, thymidine, cytidine and guanosine. Also able to transport purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Involved in nucleoside transport at basolateral membrane of kidney cells, allowing liver absorption of nucleoside metabolites. Mediates apical nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis-barrier. Mediates both the influx and efflux of hypoxanthine in skeletal muscle microvascular endothelial cells to control the amount of intracellular hypoxanthine available for xanthine oxidase-mediated ROS production. Isoform 3: Non functional nucleoside transporter protein for adenosine or thymidine transport. Does not express on cell membrane.
Protein Name Equilibrative Nucleoside Transporter 2
Hent2
36 Kda Nucleolar Protein Hnp36
Delayed-Early Response Protein 12
Equilibrative Nitrobenzylmercaptopurine Riboside-Insensitive Nucleoside Transporter
Equilibrative Nbmpr-Insensitive Nucleoside Transporter
Hydrophobic Nucleolar Protein - 36 Kda
Nucleoside Transporter - Ei-Type
Solute Carrier Family 29 Member 2
Database Links Reactome: R-HSA-83936
Reactome: R-HSA-9748787
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Localized To The Apical Membrane Of Sertoli Cells
Alternative Antibody Names Anti-Equilibrative Nucleoside Transporter 2 antibody
Anti-Hent2 antibody
Anti-36 Kda Nucleolar Protein Hnp36 antibody
Anti-Delayed-Early Response Protein 12 antibody
Anti-Equilibrative Nitrobenzylmercaptopurine Riboside-Insensitive Nucleoside Transporter antibody
Anti-Equilibrative Nbmpr-Insensitive Nucleoside Transporter antibody
Anti-Hydrophobic Nucleolar Protein - 36 Kda antibody
Anti-Nucleoside Transporter - Ei-Type antibody
Anti-Solute Carrier Family 29 Member 2 antibody
Anti-SLC29A2 antibody
Anti-DER12 antibody
Anti-ENT2 antibody
Anti-HNP36 antibody

Information sourced from Uniprot.org