| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SLC25A22 (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SLC25A22 |
| Gene ID: | 79751 |
| Uniprot ID: | GHC1_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | Specific for SLC25A22. |
| Immunogen: | A synthetic peptide from c-terminal region of human Mitochondrial glutamate carrier 1 (SLC25A22) conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Mitochondrial glutamate/H(+) symporter. Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton. Plays a role in the control of glucose-stimulated insulin secretion. |
| Protein Name | Mitochondrial Glutamate Carrier 1Gc-1Glutamate/H(+ Symporter 1Solute Carrier Family 25 Member 22 |
| Database Links | Reactome: R-HSA-428643Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Glutamate Carrier 1 antibodyAnti-Gc-1 antibodyAnti-Glutamate/H(+ Symporter 1 antibodyAnti-Solute Carrier Family 25 Member 22 antibodyAnti-SLC25A22 antibodyAnti-GC1 antibody |
Information sourced from Uniprot.org
![Immunofluorescence analysis of L929 cells using [KO Validated] SLC25A22 Rabbit polyclonal antibody (STJ119808) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/98597/382525/STJ119808_1__29834.1713150947.jpg?c=1 "Immunofluorescence analysis of L929 cells using [KO Validated] SLC25A22 Rabbit polyclonal antibody (STJ119808) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.")
